PDE5阻害薬（血流を良くして症状改善）

代表的な薬

• タダラフィル（低用量・毎日内服）

作用

• 前立腺・膀胱・骨盤血流を改善
• 排尿症状と勃起機能を同時に改善

特徴

• 排尿＋EDの両方に効果
• QOL改善効果が高い

向いている方

• 排尿症状とEDを同時に治療したい方
• 比較的若年〜活動性の高い方

注意点

• 頭痛、ほてり
• 硝酸薬内服中は使用不可

文責　加藤忍（日本泌尿器科学会専門医、藤田医科大学腎泌尿器外科客員教授）

③ PDE5 Inhibitors

(Medications that improve blood flow and relieve urinary symptoms)

Representative medication
• Tadalafil (low-dose, taken once daily)

How it works
• Improves blood flow to the prostate, bladder, and pelvic region
• Helps improve both urinary symptoms and erectile function

Key features
• Effective for both urinary symptoms and erectile dysfunction (ED)
• Provides a significant improvement in quality of life (QOL)

Who may benefit most
• Men who want to treat urinary symptoms and ED at the same time
• Relatively younger or physically active men

Points to note
• Possible side effects include headache and facial flushing
• Cannot be used by patients taking nitrate medications

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Written by
Shinobu Kato, MD, PhD
Director / Board-Certified Urologist
Visiting Professor, Department of Urology, Fujita Health University